Furotil 250mg 6pcs

Indications of Furotil 250mg Tablet

Furotil 250 is an antibiotic that treats bacterial infections in the body. It treats infections of the lungs (e.g., pneumonia), the ear, throat, nasal sinuses, the urinary tract, the skin, soft tissues, bones, and joints. It's also used to keep infections at bay during surgery. Under the supervision of a healthcare professional, Furotil 250 is administered as a drip (intravenous infusion) or as an injection directly into a vein or muscle.

Pharmacology of Furotil 250mg Tablet

Cefuroxime is a well-known and effective antibacterial agent with broad-spectrum bactericidal activity against a wide range of infections, including those that produce -lactamases. Cefuroxime is bacterial-lactamase resistant, making it effective against a wide range of ampicillin- and amoxicillin-resistant strains.

Furotil 250mg Tablet Dosage & Administration

Tablet or Suspension-

Adolescents and adults (13 years and older)-

• Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
• Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
• Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
• Secondary bacterial infections of acute bronchitis: 250-500 mg b.i.d. for 5-10 days
• Uncomplicated skin and skin structure infections: 250-500 mg b.i.d. for 10 days
• Uncomplicated urinary tract infections: 250 mg b.i.d. for 7-10 days
• Uncomplicated Gonorrhoea: 1000 mg Single dose
• Community acquired pneumonia: 250-500 mg b.i.d. for 5-10 days
• MDR Typhoid Fever: 500 mg b.i.d. for 10-14 days
• Early Lyme disease: 500 mg b.i.d. for 20 days

Paediatric Patients (3 months to 12 years)-

• Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
• Acute otitis media: 30 mg/kg/day b.i.d for 10 days
• Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
• Impetigo: 30 mg/kg/day b.i.d for 10 days

Parenteral-

• Adult: 750 mg three times daily by IM or IV injection. In severe infections, the dose can be increased up to 1.5 gm three times daily by IV injection. The frequency may be increased to four times daily, if necessary, giving total daily doses of 3 to 6 gms.
• Children (above 3 months of age): 30 - 100 mg/kg/day given in 3 or 4 equally divided doses. A dose of 60 mg/kg/day is appropriate for most infections.
• Neonate: 30 - 100 mg/kg/day given in 2 or 3 equally divided doses.
• Surgical prophylaxis: 1.5 gm by IV injection at induction of anaesthesia; up to 3 further doses of 750 mg may be given by IV/IM injection every 8 hours for high-risk procedures.
• Pneumonia: 1.5 gm IV injection twice daily for 2-3 days, followed by 500 mg twice daily (oral) for 7-10 days.
• Acute exacerbations of chronic bronchitis: 750 mg twice daily (IM or IV injection) for 2-3 days, followed by 500 mg twice daily (oral) for 5-10 days. (Duration of both parenteral and oral therapy is determined by the severity of the infection and the clinical status of the patient.)
• In Gonorrhoea: Adult: 1.5 gm as a single dose (as 2 x 750mg injections intramuscularly with different sites, e.g. each buttock).

In Meningitis:

• Adult: 3 gm IV injection three times daily.
• Children (above 3 months of age): 200-240 mg/kg/day by IV injection in 3 or 4 divided doses reduced to 100 mg/kg/day after 3 days or on clinical improvement.
• Neonate: 100 mg/kg/day by IV injection at initial dose, reduced to 50 mg/kg/day, When clinically indicated.

In bone and joint infections:

• Adult: 1.5 gm IV injection four times daily.
• Children (above 3 months of age): 150 mg/kg/day (not to exceed the maximum adult dose) in equally divided doses every 8 hours.
• The use of a freshly reconstituted solution is recommended. However, it maintains potency for at least 24 hours at room temperature or 48 hours at 5o C

Contraindications

Cefuroxime is not recommended for people who have a Cephalosporin allergy.

Furotil 250mg Tablet Side Effects

• Rash
• Vomiting
• Allergic reaction
• Increased liver enzymes
• Nausea
• Injection site reaction
• Diarrhea

Pregnancy & Lactation

Cefuroxime is classified as a pregnancy category B by the US Food and Drug Administration. However, no suitable and well-controlled studies in pregnant women have been conducted. Because animal reproduction studies do not always predict human response, this medication should only be used during pregnancy if absolutely necessary. Human milk has been found to contain cefuroxime. When Cefuroxime is given to a nursing woman, caution should be observed.

Precautions & Warnings

• Cefuroxime should be used with caution in people who take strong diuretics and have a history of colitis.
• Despite reports of cross-reactions, cephalosporin medicines can often be given safely to patients who are penicillin hypersensitive.
• Cefuroxime has demonstrated that this is unlikely to be an issue at the recommended dose levels.

Storage Conditions

Store in a cool, dry place (below 30° C), away from light & moisture. Keep out of the reach of children.